Decrease from MCQ: topiramate had trend of accentuating effect of methamphetamine to increase value of drug over money. External link. Phentermine is in a class of medications called anorectics. Retrieved 11 July Metabolic and Nutritional Disorders. Absorption of Topiramate is rapid, with peak plasma concentrations occurring at approximately 2 hours following a mg oral dose. Rustembegovic et al 56 performed an open-label trial of topiramate 50 mg twice daily for 30 days in 12 patients with alcohol dependence who had at least 1—2 tonic-clonic seizures per year. All study designs, including randomized control trials RCTs , open trials, case series, and case reports, were included for review. Craving decrease with topiramate in outpatient treatment for cocaine dependence: an open label trial.

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